HLA Class Ia and Ib Polyreactive Anti-HLA-E IgG2a Monoclonal Antibodies (TFL-006 and TFL-007) Suppress Anti-HLA IgG Production by CD19+ B Cells and Proliferation of CD4+ T Cells While Upregulating Tregs

Figure 8

Suppression of proliferation of the PHA-activated CD4+ T cells by purified culture supernatant of anti-HLA-E mAb TFL-006s (at 5 μg/ml and at 0.5 μg/ml) but not by the control mAb TFL-037 (at 5 μg/ml) (for details, see [47]).