Review Article
Immunohistopathological Findings of Severe Cutaneous Adverse Drug Reactions
Figure 1
Hematoxylin-eosin (HE) sections of toxic epidermal necrolysis (TEN) (a) and erythema multiforme (EM) (b). (a) Subepidermal bullae under full-thickness epidermal necrosis. Note: the cell-poor dermal inflammation. (b) An interface reaction pattern with infiltrates of lymphocytes and scattered necrotic keratinocytes. Lymphocyte infiltrates are much denser in EM than in TEN. Bar = 100 μm.
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