Journal of Immunology Research / 2017 / Article / Fig 1

Review Article

Immunohistopathological Findings of Severe Cutaneous Adverse Drug Reactions

Figure 1

Hematoxylin-eosin (HE) sections of toxic epidermal necrolysis (TEN) (a) and erythema multiforme (EM) (b). (a) Subepidermal bullae under full-thickness epidermal necrosis. Note: the cell-poor dermal inflammation. (b) An interface reaction pattern with infiltrates of lymphocytes and scattered necrotic keratinocytes. Lymphocyte infiltrates are much denser in EM than in TEN. Bar = 100 μm.

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