A Comprehensive Review of US FDA-Approved Immune Checkpoint Inhibitors in Urothelial Carcinoma

Table 4

Selected new or ongoing clinical trials of PD-1/PD-L1 inhibitors for the treatment of urothelial carcinoma.

NCT identifier	Interventions	Recruitment	Phases	Locations
NCT03113266	Anti-PD-1 monoclonal antibody	Recruiting	Phase 2	China
NCT03287050	Pembrolizumab/radiation	Not yet recruiting	Early phase 1	United States
NCT03240016	Pembrolizumab/abraxane	Not yet recruiting	Phase 2	United States
NCT02807636	Atezolizumab/carboplatin/gemcitabine/cisplatin/placebo	Recruiting	Phase 3	Globe
NCT02853305	Pembrolizumab/cisplatin/carboplatin/gemcitabine	Recruiting	Phase 3	Globe
NCT03219775	Nivolumab/ipilimumab	Recruiting	Phase 2	Germany
NCT02500121	Pembrolizumab/placebo	Recruiting	Phase 2	United States
NCT02450331	Atezolizumab	Recruiting	Phase 3	Globe
NCT03115801	Atezolizumab/radiation	Recruiting	Phase 2	United States
NCT03244384	Pembrolizumab/clinical observation/biomarker analysis	Recruiting	Phase 3	United States
NCT02451423	Atezolizumab dose level 1/dose level 2/dose level 3	Recruiting	Phase 2	United States
NCT02897765	NEO-PV-01/nivolumab/adjuvant	Recruiting	Phase 1	United States
NCT02845323	Nivolumab + urelumab/nivolumab monotherapy	Recruiting	Phase 2	United States
NCT02736266	Pembrolizumab	Recruiting	Phase 2	Italy
NCT03237780	Atezolizumab/eribulin mesylate/biomarker analysis	Not yet recruiting	Phase 2	United States