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Journal of Immunology Research
Volume 2017, Article ID 9253208, 6 pages
https://doi.org/10.1155/2017/9253208
Research Article

Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum

1College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China
2College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China

Correspondence should be addressed to Daojun Xu; moc.361@92nujoadux and Qing Yang; nc.ude.uanuh@nhgnaygniq

Received 2 August 2016; Accepted 13 December 2016; Published 9 January 2017

Academic Editor: Menaka C. Thounaojam

Copyright © 2017 Lunbo Tan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Colostrum is the main external resource providing piglets with nutrients and maternal immune molecules. Astragalus polysaccharides (APS) have been used as immunopotentiators in vitro and several animal models. This study aimed to determine the effects of APS on immune factors in sow colostrum and milk. The sow diet was supplemented with APS one week before the expected delivery date. Colostrum and milk were collected and designated as 0 h- (onset of parturition), 12 h-, and 24 h-colostrum and 36 h-milk postpartum. Samples were measured using porcine immunoglobulin (Ig) G, IgM, classical swine fever virus antibody (CSFV Ab), epidermal growth factor (EGF), and insulin-like growth factor- (IGF-) 1 ELISA Quantitation Kits. Dietary supplementation of APS significantly enhanced the presence of IgG, IgM, EGF, and IGF-1 in 0 h-colostrum (). The blocking rates of CSFV Ab were increased in samples from APS-supplemented sow when compared to those from the matched samples without APS treatment. The results indicate that supplement of APS could improve the immune components in sow colostrum and/or milk; and status of some specific vaccination could be determined through using colostrum or early milk in sow.