Table of Contents Author Guidelines Submit a Manuscript
Journal of Immunology Research
Volume 2017, Article ID 9489383, 12 pages
https://doi.org/10.1155/2017/9489383
Research Article

Propyl Gallate Exerts an Antimigration Effect on Temozolomide-Treated Malignant Glioma Cells through Inhibition of ROS and the NF-κB Pathway

1Department of Neurosurgery, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan
2College of Medicine, Chang Gung University, Tao-Yuan 33302, Taiwan
3Department of Medical Research, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan
4Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
5Department of Microbiology, Immunology and Biopharmaceuticals, College of Life Sciences, National Chiayi University, Chiayi City 60004, Taiwan

Correspondence should be addressed to Ching-Hsein Chen; wt.ude.uycn.liam@hcnehc

Received 21 March 2017; Revised 23 June 2017; Accepted 28 June 2017; Published 14 September 2017

Academic Editor: Daniel Ortuño-Sahagún

Copyright © 2017 Jen-Tsung Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Omuro and L. M. DeAngelis, “Glioblastoma and other malignant gliomas: a clinical review,” The Journal of the American Medical Association, vol. 310, no. 17, pp. 1842–1850, 2013. View at Publisher · View at Google Scholar · View at Scopus
  2. B. Huang, H. Zhang, L. Gu et al., “Advances in immunotherapy for glioblastoma multiforme,” Journal of Immunology Research, vol. 2017, Article ID 3597613, 11 pages, 2017. View at Publisher · View at Google Scholar
  3. O. J. Zarnett, A. Sahgal, J. Gosio et al., “Treatment of elderly patients with glioblastoma: a systematic evidence-based analysis,” JAMA Neurology, vol. 72, no. 5, pp. 589–596, 2015. View at Publisher · View at Google Scholar · View at Scopus
  4. E. M. Caspani, P. H. Crossley, C. Redondo-Garcia, and S. Martinez, “Glioblastoma: a pathogenic crosstalk between tumor cells and pericytes,” PLoS One, vol. 9, no. 7, article e101402, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. Y. Narita, “Bevacizumab for glioblastoma,” Therapeutics and Clinical Risk Management, vol. 11, pp. 1759–1765, 2015. View at Publisher · View at Google Scholar · View at Scopus
  6. P. Fu, Y. S. He, Q. Huang et al., “Bevacizumab treatment for newly diagnosed glioblastoma: systematic review and meta-analysis of clinical trials,” Molecular and Clinical Oncology, vol. 4, no. 5, pp. 833–838, 2016. View at Publisher · View at Google Scholar
  7. A. Lena, M. Rechichi, A. Salvetti et al., “Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells,” Journal of Translational Medicine, vol. 7, p. 13, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Bache, S. Bernhardt, S. Passin et al., “Betulinic acid derivatives NVX-207 and B10 for treatment of glioblastoma--an in vitro study of cytotoxicity and radiosensitization,” International Journal of Molecular Sciences, vol. 15, no. 11, pp. 19777–19790, 2014. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Vartanian, S. K. Singh, S. Agnihotri et al., “GBM’s multifaceted landscape: highlighting regional and microenvironmental heterogeneity,” Neuro-Oncology, vol. 16, no. 9, pp. 1167–1175, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. T. Tasaki, M. Fujita, T. Okuda et al., “MET expressed in glioma stem cells is a potent therapeutic target for glioblastoma multiforme,” Anticancer Research, vol. 36, no. 7, pp. 3571–3577, 2016. View at Google Scholar
  11. C. H. Chen, Y. J. Chang, M. S. Ku, K. T. Chung, and J. T. Yang, “Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation,” Journal of Molecular Medicine, vol. 89, no. 3, pp. 303–315, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. H. Hamishehkar, S. Khani, S. Kashanian, J. Ezzati Nazhad Dolatabadi, and M. Eskandani, “Geno- and cytotoxicity of propyl gallate food additive,” Drug and Chemical Toxicology, vol. 37, no. 3, pp. 241–246, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. E. J. Jo, S. J. Park, and B. C. Kim, “Propyl gallate sensitizes human lung cancer cells to cisplatin-induced apoptosis by targeting heme oxygenase-1 for TRC8-mediated degradation,” European Journal of Pharmacology, vol. 788, pp. 321–327, 2016. View at Publisher · View at Google Scholar · View at Scopus
  14. C. H. Chen, W. C. Lin, C. N. Kuo, and F. J. Lu, “Role of redox signaling regulation in propyl gallate-induced apoptosis of human leukemia cells,” Food and Chemical Toxicology, vol. 49, no. 2, pp. 494–501, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. B. R. You and W. H. Park, “The enhancement of propyl gallate-induced apoptosis in HeLa cells by a proteasome inhibitor MG132,” Oncology Reports, vol. 25, no. 3, pp. 871–877, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. J. M. Zheng, X. C. Chen, M. Lin et al., “Mechanism of the reduction of cerebral ischemic-reperfusion injury through inhibiting the activity of NF-kappaB by propyl gallate,” Yao Xue Xue Bao, vol. 46, no. 2, pp. 158–164, 2011. View at Google Scholar
  17. S. S. Taparia and A. Khanna, “Procyanidin-rich extract of natural cocoa powder causes ROS mediated caspase-3 dependent apoptosis and reduction of pro-MMP-2 in epithelial ovarian carcinoma cell lines,” Biomedicine & Pharmacotherapy, vol. 83, pp. 130–140, 2016. View at Publisher · View at Google Scholar · View at Scopus
  18. L. G. Toussaint 3rd, A. E. Nilson, J. M. Goble et al., “Galectin-1, a gene preferentially expressed at the tumor margin, promotes glioblastoma cell invasion,” Molecular Cancer, vol. 11, p. 32, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Gil, Y. K. Kim, K. E. Kim, W. Kim, C. S. Park, and K. J. Lee, “Cellular prion protein regulates invasion and migration of breast cancer cells through MMP-9 activity,” Biochemical and Biophysical Research Communications, vol. 470, no. 1, pp. 213–219, 2016. View at Google Scholar
  20. S. Dayal, J. Zhou, P. Manivannan et al., “RNase L suppresses androgen receptor signaling, cell migration and matrix metalloproteinase activity in prostate cancer cells,” International Journal of Molecular Sciences, vol. 18, no. 3, 2017. View at Publisher · View at Google Scholar
  21. F. Y. Zhang, Y. Hu, Z. Y. Que et al., “Shikonin inhibits the migration and invasion of human glioblastoma cells by targeting phosphorylated beta-catenin and phosphorylated PI3K/Akt: a potential mechanism for the anti-glioma efficacy of a traditional Chinese herbal medicine,” International Journal of Molecular Sciences, vol. 16, no. 10, pp. 23823–23848, 2015. View at Publisher · View at Google Scholar · View at Scopus
  22. M. V. Rojiani, J. Alidina, N. Esposito, and A. M. Rojiani, “Expression of MMP-2 correlates with increased angiogenesis in CNS metastasis of lung carcinoma,” International Journal of Clinical and Experimental Pathology, vol. 3, no. 8, pp. 775–781, 2010. View at Google Scholar
  23. T. R. Hurd, M. DeGennaro, and R. Lehmann, “Redox regulation of cell migration and adhesion,” Trends in Cell Biology, vol. 22, no. 2, pp. 107–115, 2012. View at Publisher · View at Google Scholar
  24. P. B. Pun, J. Lu, and S. Moochhala, “Involvement of ROS in BBB dysfunction,” Free Radical Research, vol. 43, no. 4, pp. 348–364, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. M. A. Cichon and D. C. Radisky, “ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of snail,” Oncotarget, vol. 5, no. 9, pp. 2827–2838, 2014. View at Publisher · View at Google Scholar
  26. S. Galadari, A. Rahman, S. Pallichankandy, and F. Thayyullathil, “Reactive oxygen species and cancer paradox: to promote or to suppress?” Free Radical Biology & Medicine, vol. 104, pp. 144–164, 2017. View at Publisher · View at Google Scholar
  27. A. Panday, M. K. Sahoo, D. Osorio, and S. Batra, “NADPH oxidases: an overview from structure to innate immunity-associated pathologies,” Cellular & Molecular Immunology, vol. 12, no. 1, pp. 5–23, 2015. View at Publisher · View at Google Scholar · View at Scopus
  28. H. U. Simon, A. Haj-Yehia, and F. Levi-Schaffer, “Role of reactive oxygen species (ROS) in apoptosis induction,” Apoptosis, vol. 5, no. 5, pp. 415–418, 2000. View at Google Scholar
  29. D. Y. Rhyu, Y. Yang, H. Ha et al., “Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells,” Journal of American Society Nephrology, vol. 16, no. 3, pp. 667–675, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. S. Lian, Y. Xia, P. N. Khoi et al., “Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-small ka, CyrillicB, and AP-1 pathways in human endothelial cells,” Toxicology, vol. 338, pp. 104–116, 2015. View at Publisher · View at Google Scholar · View at Scopus
  31. W. T. Chiu, S. C. Shen, J. M. Chow, C. W. Lin, L. T. Shia, and Y. C. Chen, “Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation,” Neurobiology of Disease, vol. 37, no. 1, pp. 118–129, 2010. View at Publisher · View at Google Scholar · View at Scopus
  32. G. R. Martins, G. B. Gelaleti, M. G. Moschetta, L. B. Maschio-Signorini, and D. A. Zuccari, “Proinflammatory and anti-inflammatory cytokines mediated by NF-kappaB factor as prognostic markers in mammary tumors,” Mediators of Inflammation, vol. 2016, Article ID 9512743, 10 pages, 2016. View at Publisher · View at Google Scholar · View at Scopus
  33. W. Xia, H. Tian, X. Cai et al., “Inhibition of SUMO-specific protease 1 induces apoptosis of astroglioma cells by regulating NF-kappaB/Akt pathways,” Gene, vol. 595, no. 2, pp. 175–179, 2016. View at Publisher · View at Google Scholar · View at Scopus
  34. M. Shinohara, Y. Adachi, J. Mitsushita et al., “Reactive oxygen generated by NADPH oxidase 1 (Nox1) contributes to cell invasion by regulating matrix metalloprotease-9 production and cell migration,” The Journal of Biological Chemistry, vol. 285, no. 7, pp. 4481–4488, 2010. View at Publisher · View at Google Scholar · View at Scopus
  35. H. J. Jung, S. J. Kim, W. K. Jeon et al., “Anti-inflammatory activity of n-propyl gallate through down-regulation of NF-kappaB and JNK pathways,” Inflammation, vol. 34, no. 5, pp. 352–361, 2011. View at Publisher · View at Google Scholar · View at Scopus
  36. A. Mähler, S. Mandel, M. Lorenz et al., “Epigallocatechin-3-gallate: a useful, effective and safe clinical approach for targeted prevention and individualized trearment of neurological diseases?” The EPMA Journal, vol. 4, no. 1, p. 5, 2013. View at Publisher · View at Google Scholar
  37. L. Wu, Q. L. Zhang, X. Y. Zhang et al., “Pharmacokinetics and blood-brain barrier penetration of (+)-catechin and (-)-epicatechin in rats by microdialysis sampling coupled to high-performance liquid chromatography with chemiluminescence detection,” Journal of Agricultural and Food Chemistry, vol. 60, no. 37, pp. 9377–9383, 2012. View at Publisher · View at Google Scholar · View at Scopus
  38. J. T. Yang, Z. L. Li, Y. J. Wu, F. J. Lu, and C. H. Chen, “An oxidative stress mechanism of shikonin in human glioma cells,” PLoS One, vol. 9, no. 4, article e84180, 2014. View at Publisher · View at Google Scholar · View at Scopus
  39. S. Y. Wu, H. S. Hou, Y. S. Sun, J. Y. Cheng, and K. Y. Lo, “Correlation between cell migration and reactive oxygen species under electric field stimulation,” Biomicrofluidics, vol. 9, no. 5, article 054120, 2015. View at Publisher · View at Google Scholar · View at Scopus
  40. Y. Zhi, Y. Duan, X. Zhou et al., “NF-κB signaling pathway confers neuroblastoma cells migration and invasion ability via the regulation of CXCR4,” Medical Science Monitor, vol. 20, pp. 2746–2752, 2014. View at Publisher · View at Google Scholar · View at Scopus
  41. M. J. Morgan and Z. Liu, “Crosstalk of reactive oxygen species and NF-κB signaling,” Cell Research, vol. 21, no. 1, pp. 103–115, 2011. View at Publisher · View at Google Scholar · View at Scopus