Adrenomedullin Regulates IL-1β Gene Expression in F4/80+ Macrophages during Synovial Inflammation

Figure 3

Real-time polymerase chain reaction (PCR) analysis for interleukin- (IL-) 1β, adrenomedullin (AM), receptor activity-modifying protein 2 (RAMP2), and RAMP3 gene expression in F4/80-negative and -positive cells derived from inflamed synovial tissue. (a) IL-1β, (b) adrenomedullin (AM), (c) receptor activity-modifying protein 2 (RAMP2), and (d) RAMP3 gene expression in ST obtained from the control and dislocated side of a patellar surgical dislocation model generated in C57BL/6J mice. Statistically significant difference between F4/80-negative and F4/80-positive fractions. All data are presented as the mean ± standard error ().

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