Research Article

Two-Parametric Immunological Score Development for Assessing Renal Involvement and Disease Activity in Systemic Lupus Erythematosus

Table 2

Odds ratios (ORs) when combining anti-dsDNA and anti-C1q antibodies for the association with lupus nephritis (LN), LN activity and disease activity. Thresholds are based on clustering sections described in Figure 4.

SectionsDisease activity odds ratios (95% CI)Lupus nephritis odds ratios (95% CI)Lupus nephritis activity odds ratios (95% CI)

Cluster sections 1–40.47 (0.23–0.94)0.35 (0.20–0.61)0.27 (0.09–0.85)
Cluster sections 5–76.3 (3.0–13.3)5.6 (2.9-10.7)10.8 (3.4–33.8)
Cluster sections 8 and 910.6 (3.0–37.3)28.7 (4.5–178.1)8.2 (1.7–38.1)