Journal of Immunology Research
Volume 2018, Article ID 1628620, 9 pages
https://doi.org/10.1155/2018/1628620
Obesity May Provide Pro-ILC3 Development Inflammatory Environment in Asthmatic Children
1Department of Laboratory Medicine, The Third Affiliated Hospital of Soochow University, Changzhou 213003, China
2Department of Orthopaedics, The Third Affiliated Hospital of Soochow University, Changzhou 213003, China
3Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China
4Department of Orthopaedics, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu Province 212001, China
5Department of Biomedical Science, School of Allied Health Sciences, University of Cape Coast, Ghana
6Department of Immunology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu Province 212013, China
Correspondence should be addressed to Weifeng Shi; moc.361@31176fws
Received 19 January 2018; Revised 27 August 2018; Accepted 25 September 2018; Published 6 December 2018
Academic Editor: Eyad Elkord
Copyright © 2018 Yumin Wu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Linked References
- A. Guilherme, J. V. Virbasius, V. Puri, and M. P. Czech, “Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes,” Nature Reviews Molecular Cell Biology, vol. 9, no. 5, pp. 367–377, 2008. View at Publisher · View at Google Scholar · View at Scopus
- T. Mandviwala, U. Khalid, and A. Deswal, “Obesity and cardiovascular disease: a risk factor or a risk marker?” Current Atherosclerosis Reports, vol. 18, no. 5, p. 21, 2016. View at Publisher · View at Google Scholar · View at Scopus
- E. S. Ford, “The epidemiology of obesity and asthma,” The Journal of Allergy and Clinical Immunology, vol. 115, no. 5, pp. 897–909, 2005. View at Publisher · View at Google Scholar · View at Scopus
- N. D. Ford, S. A. Patel, and K. M. V. Narayan, “Obesity in low- and middle-income countries: burden, drivers, and emerging challenges,” Annual Review of Public Health, vol. 38, no. 1, pp. 145–164, 2017. View at Publisher · View at Google Scholar · View at Scopus
- A. B. Becker and E. M. Abrams, “Asthma guidelines: the global initiative for asthma in relation to national guidelines,” Current Opinion in Allergy and Clinical Immunology, vol. 17, no. 2, pp. 99–103, 2017. View at Publisher · View at Google Scholar · View at Scopus
- F. Blasi, G. Bettoncelli, G. W. Canonica et al., “The management of asthma in the phenotype and biomarker era: the proposal of a new diagnostic-therapeutic model,” The Journal of Asthma, vol. 53, no. 7, pp. 665–7, 2016. View at Publisher · View at Google Scholar · View at Scopus
- T. D. Kanneganti and V. D. Dixit, “Immunological complications of obesity,” Nature Immunology, vol. 13, no. 8, pp. 707–712, 2012. View at Publisher · View at Google Scholar · View at Scopus
- A. J. Cox, N. P. West, and A. W. Cripps, “Obesity, inflammation, and the gut microbiota,” The Lancet Diabetes & Endocrinology, vol. 3, no. 3, pp. 207–215, 2015. View at Publisher · View at Google Scholar · View at Scopus
- G. Pelaia, A. Vatrella, M. T. Busceti et al., “Cellular mechanisms underlying eosinophilic and neutrophilic airway inflammation in asthma,” Mediators of Inflammation, vol. 2015, Article ID 879783, 8 pages, 2015. View at Publisher · View at Google Scholar · View at Scopus
- J. E. Fergeson, S. S. Patel, and R. F. Lockey, “Acute asthma, prognosis, and treatment,” The Journal of Allergy and Clinical Immunology, vol. 139, no. 2, pp. 438–447, 2017. View at Publisher · View at Google Scholar · View at Scopus
- C. Irvin, I. Zafar, J. Good et al., “Increased frequency of dual-positive TH2/TH17 cells in bronchoalveolar lavage fluid characterizes a population of patients with severe asthma,” The Journal of Allergy and Clinical Immunology, vol. 134, no. 5, pp. 1175–1186.e7, 2014, e7. View at Publisher · View at Google Scholar · View at Scopus
- L. van Rijt, H. von Richthofen, and R. van Ree, “Type 2 innate lymphoid cells: at the cross-roads in allergic asthma,” Seminars in Immunopathology, vol. 38, no. 4, pp. 483–496, 2016. View at Publisher · View at Google Scholar · View at Scopus
- M. Ebbo, A. Crinier, F. Vély, and E. Vivier, “Innate lymphoid cells: major players in inflammatory diseases,” Nature Reviews. Immunology, vol. 17, no. 11, pp. 665–678, 2017. View at Publisher · View at Google Scholar · View at Scopus
- C. Symowski and D. Voehringer, “Interactions between innate lymphoid cells and cells of the innate and adaptive immune system,” Frontiers in Immunology, vol. 8, p. 1422, 2017. View at Publisher · View at Google Scholar · View at Scopus
- M. M. Shikhagaie, K. Germar, S. M. Bal, X. R. Ros, and H. Spits, “Innate lymphoid cells in autoimmunity: emerging regulators in rheumatic diseases,” Nature Reviews Rheumatology, vol. 13, no. 3, pp. 164–173, 2017. View at Publisher · View at Google Scholar · View at Scopus
- C. S. N. Klose, M. Flach, L. Möhle et al., “Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages,” Cell, vol. 157, no. 2, pp. 340–356, 2014. View at Publisher · View at Google Scholar · View at Scopus
- L. Y. Drake, K. Iijima, K. Bartemes, and H. Kita, “Group 2 innate lymphoid cells promote an early antibody response to a respiratory antigen in mice,” The Journal of Immunology, vol. 197, no. 4, pp. 1335–1342, 2016. View at Publisher · View at Google Scholar · View at Scopus
- R. J. Cuthbert, E. M. Fragkakis, R. Dunsmuir et al., “Brief report: group 3 innate lymphoid cells in human enthesis,” Arthritis & Rheumatology, vol. 69, no. 9, pp. 1816–1822, 2017. View at Publisher · View at Google Scholar · View at Scopus
- S. Wang, P. Xia, Y. Chen et al., “Regulatory innate lymphoid cells control innate intestinal inflammation,” Cell, vol. 171, no. 1, pp. 201–216.e18, 2017. View at Publisher · View at Google Scholar · View at Scopus
- D. Engelbertsen and A. H. Lichtman, “Innate lymphoid cells in atherosclerosis,” European Journal of Pharmacology, vol. 816, pp. 32–36, 2017. View at Publisher · View at Google Scholar · View at Scopus
- A. Geremia, C. V. Arancibia-Cárcamo, M. P. P. Fleming et al., “IL-23–responsive innate lymphoid cells are increased in inflammatory bowel disease,” The Journal of Experimental Medicine, vol. 208, no. 6, pp. 1127–1133, 2011. View at Publisher · View at Google Scholar · View at Scopus
- R. Sabat and K. Wolk, “Deciphering the role of interleukin-22 in metabolic alterations,” Cell & Bioscience, vol. 5, no. 1, p. 68, 2015. View at Publisher · View at Google Scholar · View at Scopus
- H. Y. Kim, H. J. Lee, Y. J. Chang et al., “Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity,” Nature Medicine, vol. 20, no. 1, pp. 54–61, 2014. View at Publisher · View at Google Scholar · View at Scopus
- B. F. Zhou and Cooperative Meta-Analysis Group of the Working Group on Obesity in China, “Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults--study on optimal cut-off points of body mass index and waist circumference in Chinese adults,” Biomedical and Environmental Sciences, vol. 15, no. 1, pp. 83–96, 2002. View at Google Scholar
- H. Kimura, S. Konno, H. Makita et al., “Serum periostin is associated with body mass index and allergic rhinitis in healthy and asthmatic subjects,” Allergology International, vol. 67, no. 3, pp. 357–363, 2018. View at Publisher · View at Google Scholar · View at Scopus
- V. P. Singh, U. Mabalirajan, K. Pratap et al., “House dust mite allergen causes certain features of steroid resistant asthma in high fat fed obese mice,” International Immunopharmacology, vol. 55, pp. 20–27, 2018. View at Publisher · View at Google Scholar · View at Scopus
- S. H. Kim, E. R. Sutherland, and E. W. Gelfand, “Is there a link between obesity and asthma?” Allergy, Asthma & Immunology Research, vol. 6, no. 3, pp. 189–195, 2014. View at Publisher · View at Google Scholar · View at Scopus
- A. van Huisstede, A. Rudolphus, M. Castro Cabezas et al., “Effect of bariatric surgery on asthma control, lung function and bronchial and systemic inflammation in morbidly obese subjects with asthma,” Thorax, vol. 70, no. 7, pp. 659–667, 2015. View at Publisher · View at Google Scholar · View at Scopus
- D. Rastogi, K. Bhalani, C. B. Hall, and C. R. Isasi, “Association of pulmonary function with adiposity and metabolic abnormalities in urban minority adolescents,” Annals of the American Thoracic Society, vol. 11, no. 5, pp. 744–752, 2014. View at Publisher · View at Google Scholar · View at Scopus
- E. Forno, Y. Y. Han, R. H. Muzumdar, and J. C. Celedón, “Insulin resistance, metabolic syndrome, and lung function in US adolescents with and without asthma,” The Journal of Allergy and Clinical Immunology, vol. 136, no. 2, pp. 304–311.e8, 2015, e8. View at Publisher · View at Google Scholar · View at Scopus
- S. G. Wendell, C. Baffi, and F. Holguin, “Fatty acids, inflammation, and asthma,” The Journal of Allergy and Clinical Immunology, vol. 133, no. 5, pp. 1255–1264, 2014. View at Publisher · View at Google Scholar · View at Scopus
- L. Steinberg, I. Aldea, and E. Messias, “Asthma, depression, and suicidality,” The Journal of Nervous and Mental Disease, vol. 203, no. 9, pp. 664–9, 2015. View at Publisher · View at Google Scholar · View at Scopus
- M. L. Manni, S. Mandalapu, K. J. McHugh, M. M. Elloso, P. L. Dudas, and J. F. Alcorn, “Molecular mechanisms of airway hyperresponsiveness in a murine model of steroid-resistant airway inflammation,” Journal of Immunology, vol. 196, no. 3, pp. 963–977, 2016. View at Publisher · View at Google Scholar · View at Scopus
- M. Kudo, A. C. Melton, C. Chen et al., “IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction,” Nature Medicine, vol. 18, no. 4, pp. 547–554, 2012. View at Publisher · View at Google Scholar · View at Scopus
- J. Klier, S. Geis, J. Steuer et al., “A comparison of nanoparticullate CpG immunotherapy with and without allergens in spontaneously equine asthma-affected horses, an animal model,” Immunity, Inflammation and Disease, vol. 6, no. 1, pp. 81–96, 2018. View at Publisher · View at Google Scholar · View at Scopus
- S. Svenningsen and P. Nair, “Asthma endotypes and an overview of targeted therapy for asthma,” Frontiers in Medicine, vol. 4, p. 158, 2017. View at Publisher · View at Google Scholar
- H. Spits, J. H. Bernink, and L. Lanier, “NK cells and type 1 innate lymphoid cells: partners in host defense,” Nature Immunology, vol. 17, no. 7, pp. 758–764, 2016. View at Publisher · View at Google Scholar · View at Scopus
- R. G. J. K. Wolterink, A. KleinJan, M. van Nimwegen et al., “Pulmonary innate lymphoid cells are major producers of IL-5 and IL-13 in murine models of allergic asthma,” European Journal of Immunology, vol. 42, no. 5, pp. 1106–1116, 2012. View at Publisher · View at Google Scholar · View at Scopus
- M. Salimi, J. L. Barlow, S. P. Saunders et al., “A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis,” The Journal of Experimental Medicine, vol. 210, no. 13, pp. 2939–2950, 2013. View at Publisher · View at Google Scholar · View at Scopus
- M. R. Karta, D. H. Broide, and T. A. Doherty, “Insights into group 2 innate lymphoid cells in human airway disease,” Current Allergy and Asthma Reports, vol. 16, no. 1, p. 8, 2016. View at Publisher · View at Google Scholar · View at Scopus
- E. Montaldo, K. Juelke, and C. Romagnani, “Group 3 innate lymphoid cells (ILC3s): origin, differentiation, and plasticity in humans and mice,” European Journal of Immunology, vol. 45, no. 8, pp. 2171–2182, 2015. View at Publisher · View at Google Scholar · View at Scopus
- T. Glatzer, M. Killig, J. Meisig et al., “RORγt+ innate lymphoid cells acquire a proinflammatory program upon engagement of the activating receptor NKp44,” Immunity, vol. 38, no. 6, pp. 1223–1235, 2013. View at Publisher · View at Google Scholar · View at Scopus
- K. Juelke and C. Romagnani, “Differentiation of human innate lymphoid cells (ILCs),” Current Opinion in Immunology, vol. 38, pp. 75–85, 2016. View at Publisher · View at Google Scholar · View at Scopus
- M. Ahmed and S. L. Gaffen, “IL-17 in obesity and adipogenesis,” Cytokine & Growth Factor Reviews, vol. 21, no. 6, pp. 449–453, 2010. View at Publisher · View at Google Scholar · View at Scopus
- L. A. Tesmer, S. K. Lundy, S. Sarkar, and D. A. Fox, “Th17 cells in human disease,” Immunological Reviews, vol. 223, no. 1, pp. 87–113, 2008. View at Publisher · View at Google Scholar · View at Scopus
- S. Ilavská, M. Horváthová, M. Szabová et al., “Association between the human immune response and body mass index,” Human Immunology, vol. 73, no. 5, pp. 480–5, 2012. View at Publisher · View at Google Scholar · View at Scopus