Clinical Study

Host Immunological Effects of Partial Splenic Embolization in Patients with Liver Cirrhosis

Table 2

Changes of various parameters before and after 4 weeks of PSE.

Pre-PSEPost-PSE

Ammonia (mg/dl)82.1 ± 9451.0 ± 430.1140
Total bilirubin (g/dl)1.5 ± 0.91.6 ± 1.20.6130
Direct bilirubin (g/dl)0.6 ± 0.50.7 ± 0.90.2650
Albumin (mg/dl)3.2 ± 0.63.1 ± 0.60.1050
AST (IU/l)52.1 ± 3058.3 ± 440.3890
ALT (IU/l)34.8 ± 2732.5 ± 280.0890
Total cholesterol (mg/dl)130.2 ± 30127.4 ± 210.9650
Blood urea nitrogen (mg/dl)16.6 ± 815.0 ± 60.1050
Creatinine (mg/dl)0.8 ± 0.30.8 ± 0.20.1300
Prothrombin time (%)65.8 ± 1469.7 ± 130.013
White blood cell (/mm3)2945.4 ± 14714704.6 ± 17300.001
Segment (/mm3)1791.2 ± 9542809.3 ± 9120.009
Lymphocyte (/mm3)607.2 ± 2151038.0 ± 4510.006
Monocyte (/mm3)245.9 ± 70440.9 ± 1030.001
Platelets (×104/mm3)4.32 ± 1.58.95 ± 5.00.001
AFP (ng/ml)2561.3 ± 570419806.0 ± 395330.0679
AFP-L3 (%)19.3 ± 2226.2 ± 310.1088
DCP (AU/ml)325.2 ± 677364.5 ± 4901.0000
Child-Pugh score7.6 ± 1.97.4 ± 1.90.4174

PSE: partial splenic embolization; AST: aspartate aminotransferase; ALT: alanine aminotransferase; AFP: alpha-fetoprotein; DCP: des-gamma carboxyprothrombin. Statistically different compared with Wilcoxon’s signed-rank sum test.