Research Article

Acute Neuroinflammatory Response in the Substantia Nigra Pars Compacta of Rats after a Local Injection of Lipopolysaccharide

Figure 10

Leukocyte infiltration. Representative micrographs showing the H&E staining and TH immunohistochemistry of the substantia nigra of untreated control rats and experimental rats at 24 and 168 h after LPS injection. The micrographs were taken at 3.2 mm from the interaural midpoint on the dorsal-ventral axis of the rat brain atlas by Paxinos and Watson [50]. The black square on 5x micrographs indicates the area where 63x amplification was taken. Arrowheads indicate leukocyte infiltration, and arrows indicate microglia/macrophages.