Natural Killer Cells from Malignant Pleural Effusion Are Endowed with a Decidual-Like Proangiogenic Polarization

Figure 2

CD49-decidual marker expression on NK cell subsets. Flow cytometric analysis demonstrated that in NK cells from patients with pleural effusions, CD49a expression was increased in the CD56^bright subset from pleural effusion (significantly in ptPE and in tmPE) as compared to PB-NK cell samples (a, b). Representative dot plots for CD49a expression on CD56^bright and CD56^dim NK subsets in healthy donors and patients with inflammatory, primary, and metastatic tumor PE are shown, respectively (c). Data are shown as mean ± SEM of 39 samples; , , , and ( values are shown).

(a)

(b)

(c)