OSU-T315 as an Interesting Lead Molecule for Novel B Cell-Specific Therapeutics

Figure 6

Antibody production after TNP-BSA immunization in mice with B cell-specific ILK deletion. The level of anti-TNP IgM (a) and IgG (b) was measured by ELISA over time in the sera of ILK WT mice (black, 8 mice) and ILK KO mice (grey, 8 mice). TNP-BSA challenges are indicated with reversed triangles. Plotted data are the means with SEM from one representative of two independently performed experiments.

(a)

(b)