High-Density Lipoprotein Reduction Differentially Modulates to Classical and Nonclassical Monocyte Subpopulations in Metabolic Syndrome Patients and in LPS-Stimulated Primary Human Monocytes In Vitro

Table 1

Demographical and metabolic parameters of the study population.

Parameters	Control	Metabolic syndrome	value
Gender (W/M)	17/25	16/28	0.313
Age (years)	49.25 ± 5.88	48.38 ± 5.47	0.296
BMI (kg/m^2)	26.12 ± 4.09	29.92 ± 5.26	0.006
Waist circumference (cm)	90.18 ± 9.22	100.41 ± 10.71	0.004
Body fat (%)	27.38 ± 7.63	33.35 ± 10.13	0.012
SBP (mmHg)	124.0 ± 2.47	126.0 ± 5.61	0.306
FBG (mg/dL)	82.37 ± 18.74	106.50 ± 23.48	0.001
Insulin (mU/L)	13.67 ± 5.30	13.90 ± 3.82	0.428
HOMA-IR	2.77 ± 1.21	3.63 ± 1.26	0.005
Total cholesterol (mg/dL)	209.04 ± 41.49	200.26 ± 32.87	0.204
Triglycerides (mg/dL)	165.04 ± 95.12	235.53 ± 95.26	0.006
HDL (mg/dL)	53.20 ± 13.34	38.53 ± 8.62	0.001
LDL (mg/dL)	116.95 ± 33.45	109.50 ± 29.46	0.203

Data are expressed as . The Shapiro-Wilk test was used to estimate normality in data distribution. Significant differences were estimated by means of performing Student’s t-test with the exception of women/men proportion in each group, which was estimated by means of the chi-squared test. Differences were considered significant when . W: women; M: men; BMI: body mass index; SBP: systolic blood pressure; FBG: fasting blood glucose; HOMA-IR: homeostatic model assessment of insulin resistance; HDL: high-density lipoprotein; LDL: low-density lipoprotein. Diagnosis of metabolic syndrome was performed according to the ATP III criteria, when three of five of the following factors were present: central obesity denoted by a waist circumference greater than 80 cm in women and 90 cm in men, circulating triglyceride , serum in men and 50 mg/dL in women, blood pressure higher than 120/80 mmHg, fasting blood .