An Increased Frequency in HLA Class I Alleles and Haplotypes Suggests Genetic Susceptibility to Influenza A (H1N1) 2009 Pandemic: A Case-Control Study

Table 1

Characteristics of influenza A H1N1/09 patients (INF-P) and contacts (INF-C) recruited during April to December 2009.

	INF-P ()	INF-C ()
Age	43.26 ± 13.86	42.21 ± 12.03
Gender [male (%)/female (%)]	78 (56.52)/60 (43.48)	105 (46.67)/120 (53.33)
Weight (kg)	83.41 ± 20.45	71.00 ± 14.10	<0.01
Height (m)	1.64 ± 0.10	1.59 ± 0.09	<0.01
BMI	30.88 ± 6.92	27.85 ± 4.86	0.01
Smoking (Y/N, %)	45.65/54.35	30.61/69.39	0.02
Comorbidities (%)
Neurological disease	25 (18.11)	33 (14.66)
Asthma	2 (1.44)	6 (2.66)
Cancer	1 (0.72)	0 (0.00)
Hypertension	8 (5.79)	17 (7.55)
Symptomatology (%)
Fever (>38°C)	104 (75.36)	0 (0.00)
Cough	72 (52.17)	0 (0.00)
Nasal congestion	17 (12.31)	0 (0.00)
Rhinorrhea	39 (28.26)	0 (0.00)
Dyspnea	101 (73.18)	0 (0.00)
Region of origin; (%)
Central Mexico	106 (76.81)	155 (68.89)
North Mexico	18 (13.04)	45 (20.00)
Southeast Mexico	14 (10.14)	25 (11.11)

INF-P: influenza patients; INF-C: influenza contacts; : number of subjects; BMI: body mass index. value < 0.05 is considered significant.