Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid Arthritis

<div>Selection of ICOSL-specific VNAR domain outputs from selection against mICOSL or hICOSL tested for binding to both ligands in ELISA. Each triangle and circle denote a clone; black fill triangles are clones binding to mICOSL only, and grey fill circles are clones binding to hICOSL only; open circles are cross-reactive clones binding to hICOSL, and open triangles are the same clones binding to mICOSL.</div>

Journal of Immunology Research

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Figure 1: Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid Arthritis 

Figure 1 | Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid Arthritis 