PD-L1 Expression and CD8⁺ T Cell Infiltration Predict a Favorable Prognosis in Advanced Gastric Cancer

Table 2

Univariate analysis of prognostic parameters for survival in GC patients.

Prognostic parameter	HR	95% CI	value
PD-L1 (positive versus negative)	0.668	0.505–0.885	0.005
PD-1 (high versus low)	0.767	0.495–1.189	0.236
CD3 (high versus low)	0.782	0.608–1.008	0.057
CD8 (high versus low)	0.691	0.536–0.891	0.004
FOXP3 (high versus low)	1.434	1.061–1.938	0.019
Age (>60 versus ≤60)	1.057	0.820–1.363	0.668
Gender (male versus female)	0.850	0.652–1.109	0.230
Tumor location (low versus others)	0.828	0.644–1.066	0.144
Length-diameter (≥5 cm versus <5 cm)	2.012	1.542–2.624	0.000
Lauren type (diffuse versus intestinal mix)	1.340	1.023–1.753	0.033
	Perineuronal invasion (absent versus present)	0.578	0.419–0.796	0.001
Blood vessel invasion (absent versus present)		0.500	0.372–0.671	0.000
	TNM stage (I–II versus III)	0.291	0.216–0.390	0.000

HR: hazard ratio; CI: confidence interval.