Research Article

Evaluation of Soluble CD48 Levels in Patients with Allergic and Nonallergic Asthma in Relation to Markers of Type 2 and Non-Type 2 Immunity: An Observational Study

Table 2

sCD48, type 2 biomarkers, and cytokine levels according to patient categorization (see also Figure 1).

Allergic asthma ()Nonallergic asthma ()Control ()ANOVA value

sCD48 (pg/ml)1358 (1228–1632)1487 (1338–1758)1308 (1070–1581)0.007
IgE (IU)374.5 (233.8–781.5)45.5 (18.25–74.15) 40 (17.5–72.1) <0.0001
Eos count400 (250–550)150 (100–250)175 (100–250)<0.0001
IL5 (pg/ml)2.746 (2.31–3.51)2.434 (1.68–3.06)2.395 (1.52–2.86)0.009
IL17A (pg/ml)84.44 (39.97–141.6)115.5 (56.8–187.3)56.7 (29.28–84.07)<0.0001
IL33 (pg/ml)130.3 (49.46–267.5)154.9 (63.58–271.9)54 (25.73–83.78)< 0.0001
IFNg (pg/ml)5.475 (3.19–13.05)5.338 (3.47–10.68)1.768 (1.18–3.2)0.008

Data is presented as median (IQR); , , and .