Integrin α9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling

Table 3

Gene set enrichment analysis (GSEA) of ITGA9 mRNA profiling results in HCC from the TCGA database.

Pathway	Genes ()	value	value
Pathways in cancer	314	0.0000	0.0627
Regulation of actin cytoskeleton	196	0.0000	0.0678
Focal adhesion	193	0.0000	0.0679
Purine metabolism	153	0.0000	0.0953
Cell adhesion molecules cams	128	0.0000	0.0574
Lysosome	121	0.0000	0.0752
Pyrimidine metabolism	97	0.0000	0.0645
ECM receptor interaction	83	0.0000	0.0758
Arrhythmogenic right ventricular cardiomyopathy	68	0.0000	0.0576
Non-small-cell lung cancer	53	0.0000	0.0687
Vasopressin-regulated water reabsorption	41	0.0000	0.0610
Prostate cancer	87	0.0019	0.0712
Small-cell lung cancer	84	0.0020	0.0639
PPAR signaling pathway	65	0.0020	0.0636
Chemokine signaling pathway	181	0.0020	0.0701
Leukocyte transendothelial migration	107	0.0020	0.0583
Basal cell carcinoma	54	0.0020	0.0657
Valine leucine and isoleucine degradation	44	0.0038	0.0632
Hedgehog signaling pathway	54	0.0039	0.0602
Inositol phosphate metabolism	54	0.0040	0.0664