Research Article

Differential Gene Expression Profile of Human Neutrophils Cultured with Plasmodium falciparum-Parasitized Erythrocytes

Figure 2

GO enrichment analyses of significantly differentially expressed genes of neutrophils in response to iRBCs. (a) Gene sets were categorized according to molecular function (upper panel) and biological processes (lower panel). (b) Network-based gene enrichment of the most significantly enriched terms for molecular function and biological processes. The annotation modules based on STRING for GO terms and multiple testing correction methods () were performed based on NET-GE tools. (c) Biological pathways enriched in upregulated genes involved in the neutrophil response to iRBCs.