Immunoinformatics Approach for Epitope-Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus

Table 2

MHC-II alleles for the desired epitope.

Core sequence	MHC-II alleles	position	Peptide	IC50 value
TSSWGCEEY	HLA-DQA101:01/DQB105:01	1040–1054	KEHTSSWGCEEYGCL	2715
	HLA-DQA101:01/DQB105:01	1041–1055	EHTSSWGCEEYGCLA	2801
LAIDTGCLY	HLA-DRB301:01	1049–1063	EEYGCLAIDTGCLYG	194
	HLA-DRB301:01	1050–1064	EYGCLAIDTGCLYGS	195
	HLA-DRB301:01	1052–1066	GCLAIDTGCLYGSCQ	195
	HLA-DRB301:01	1051–1065	YGCLAIDTGCLYGSC	196
	HLA-DRB103:01	1049–1063	EEYGCLAIDTGCLYG	401
	HLA-DRB103:01	1050–1064	EYGCLAIDTGCLYGS	401
	HLA-DRB103:01	1051–1065	YGCLAIDTGCLYGSC	403
	HLA-DRB103:01	1052–1066	GCLAIDTGCLYGSCQ	405
	HLA-DRB301:01	1054–1068	LAIDTGCLYGSCQDV	601
	HLA-DRB301:01	1053–1067	CLAIDTGCLYGSCQD	611
	HLA-DRB103:01	1054–1068	LAIDTGCLYGSCQDV	1173
	HLA-DRB103:01	1053–1067	CLAIDTGCLYGSCQD	1200
	HLA-DRB112:01	1051–1065	YGCLAIDTGCLYGSC	1450
	HLA-DRB112:01	1050–1064	EYGCLAIDTGCLYGS	1457
	HLA-DPA101:03/DPB102:01	1049–1063	EEYGCLAIDTGCLYG	1545
	HLA-DPA101:03/DPB102:01	1051–1065	YGCLAIDTGCLYGSC	1551
	HLA-DPA101:03/DPB102:01	1050–1064	EYGCLAIDTGCLYGS	1554
	HLA-DRB112:01	1052–1066	GCLAIDTGCLYGSCQ	1561
	HLA-DPA101:03/DPB102:01	1052–1066	GCLAIDTGCLYGSCQ	1571
	HLA-DRB101:01	1052–1066	GCLAIDTGCLYGSCQ	1597
	HLA-DPA102:01/DPB101:01	1050–1064	EYGCLAIDTGCLYGS	2005
	HLA-DRB113:02	1050–1064	EYGCLAIDTGCLYGS	2117
	HLA-DPA102:01/DPB101:01	1051–1065	YGCLAIDTGCLYGSC	2123
	HLA-DRB113:02	1049–1063	EEYGCLAIDTGCLYG	2127
	HLA-DRB113:02	1051–1065	YGCLAIDTGCLYGSC	2145
	HLA-DPA102:01/DPB101:01	1052–1066	GCLAIDTGCLYGSCQ	2201
	HLA-DPA102:01/DPB101:01	1049–1063	EEYGCLAIDTGCLYG	2287
	HLA-DRB104:01	1050–1064	EYGCLAIDTGCLYGS	2673
	HLA-DRB112:01	1053–1067	CLAIDTGCLYGSCQD	2760
	HLA-DRB112:01	1054–1068	LAIDTGCLYGSCQDV	2917
	HLA-DRB112:01	1049–1063	EEYGCLAIDTGCLYG	2949