Silicone-Induced Granuloma of Breast Implant Capsule (SIGBIC): Histopathology and Radiological Correlation

Figure 7

Pathology SIGBIC with extracapsular extension: imaging findings of the same patient of Figure 6. (a) Macroscopy of the fibrous capsule. Firm-elastic masses are observed in the intracapsular face (blue arrows). (b) Microscopy. The germinal center of B and T lymphocytes is observed by optical microscopy (smaller increase to the right and larger increase to the left). It is distinguished from intracapsular SIGBIC especially by the presence of lymphocytes individualized diffusely by fibrous capsule, predominantly T lymphocyte. (c) Microscopy. Right figure shows fibro necrotic material while left stands out the extracellular silicone. (d) Immunohistochemistry. There is no CD30 reaction.

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