Three Types of Broadly Reacting Antibodies against Influenza B Viruses Induced by Vaccination with Seasonal Influenza Viruses

Figure 4

Titration of binding activity of representative Abs against various kinds of influenza viruses. Purified Fab-PP form of Abs, F113-135 (type 1), F114-191, F114-142, F114-154, F114-106 (type 2), F114-109 (type 3), F045-092 (anti-H3 Ab), F081-007 (anti-H1 Ab), and 2-3E (anti-VP4 of rotavirus antibody) were utilized in this experiment. The binding activities to six kinds of influenza B virus, one H1N1 virus, one H3N2 virus, and ovalbumin (negative control) were examined under various concentrations.