Research Article

Reduced Activity of HDAC3 and Increased Acetylation of Histones H3 in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis

Figure 3

HAT and HDAC activities in the nuclear extracts of PBMCs in RA patients and HCs. HAT activity was significantly increased in RA patients compared with HCs. HDAC activity was significantly decreased in RA patients compared to that in HCs.