Research Article
Reduced Activity of HDAC3 and Increased Acetylation of Histones H3 in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis
Table 1
Demographic and clinical characteristics of patients with RA and HCs.
| | RA patients () | HCs () |
| Age, mean (range) years | 44.1 (24–69) | 42.9 (26–63) | No. of women/no. of men | 38/10 | 36/12 | Anticyclic citrullinated protein antibodies (RU/mL) | 57 (3–200) | | Rheumatoid factor (IU/mL) | 287 (11–1580) | | C-reactive protein (mg/L) | 52.3 (3.6–127.4) | 0.8 (0.2–1.9) | DAS28 score | 4.92 (1.97–8.73) | | Disease duration, mean (range) months | 10.5 (1.3–17.8) | |
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DAS28 = 28-joint disease activity score.
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