Research Article

Reduced Activity of HDAC3 and Increased Acetylation of Histones H3 in Peripheral Blood Mononuclear Cells of Patients with Rheumatoid Arthritis

Table 1

Demographic and clinical characteristics of patients with RA and HCs.

RA patients ()HCs ()

Age, mean (range) years44.1 (24–69)42.9 (26–63)
No. of women/no. of men38/1036/12
Anticyclic citrullinated protein antibodies (RU/mL)57 (3–200)
Rheumatoid factor (IU/mL)287 (11–1580)
C-reactive protein (mg/L)52.3 (3.6–127.4)0.8 (0.2–1.9)
DAS28 score4.92 (1.97–8.73)
Disease duration, mean (range) months10.5 (1.3–17.8)

DAS28 = 28-joint disease activity score.