FGFRL1 Promotes Ovarian Cancer Progression by Crosstalk with Hedgehog Signaling

Figure 4

Silencing of FGFRL1 suppresses ovarian cancer migration in vitro and tumor growth in vivo. (a) Representative migration images of FGFRL1-silenced and control cells. Original magnification: 200x. Quantification of cells on the lower surface of the membrane was performed. Data are the means ± SD. (b) Representative wound healing images of FGFRL1-silenced and control cells at 0 and 24 h, respectively. The black line outlined the cell boundary. Quantification of wound healing rates was analyzed. Data are the means ± SD. (c) Mice in the sh-FGFRL1 group showed relatively larger tumors compared with those in the control group. ; .

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