Hypocomplementemia as a Risk Factor for Organ Damage Accrual in Patients with Systemic Lupus Erythematosus

Table 1

Demographic and serological descriptors of SLE patients with and without hypocomplementemia (HC).

	NC ()	HC ()	value
Male	7 (21.2%)	6 (8.7%)	0.076
Female	26 (78.8%)	63 (91.3%)
Age at first visit			<0.001
Diagnostic delay (years)	2 (IQR 0, 5)	1 (IQR 0, 4)	0.494
Follow-up in years	7 (IQR 3, 13)	12 (IQR 6, 22)	0.017
Smoking ever	20 (66.7%)	39 (59.1%)	0.480
Years smoking	20 (IQR 15, 30)	20 (IQR 13, 26)	0.886
Waist circumference			0.048
Anti-dsDNA pos. ever	12 (36.4)	50 (72.5)	<0.001
Antiphospholipid Ab	13 (39.4)	51 (73.9)	0.001
Lupus anticoagulant pos.	2 (6.1)	12 (17.4)	0.114
aCL-IgG	12 (36.4)	42 (60.9)	0.020
aCL-IgM	8 (24.2)	32 (46.4)	0.032
Low C3 or C4 ever	—	69 (100)	—
Low C3 + C4 ever	—	33 (47.8)	—
Low C3 ever	—	67 (97.1)	—
No. of low C3 episodes	—	8 (IQR 4, 14)	<0.001
Low C4 ever	—	36 (52.2)	—
No. of low C4 episodes	—	4 (IQR 2, 9)	<0.001

Figures indicate median with interquartile range or numbers (%).