Research Article

Hei-Gu-Teng Zhuifenghuoluo Granule Modulates IL-12 Signal Pathway to Inhibit the Inflammatory Response in Rheumatoid Arthritis

Figure 8

Schematic diagram depicting how HGT modulates the IL-12 signaling pathway to inhibit the inflammatory response in rheumatoid arthritis. By inhibiting IL-12R, HGT could inhibit STAT4 and then inhibit the inflammation, meanwhile, decreasing TNF-α and IFN-γ.