Effects of Systemic Simvastatin on the Concentrations of Visfatin, Tumor Necrosis Factor-α, and Interleukin-6 in Gingival Crevicular Fluid in Patients with Type 2 Diabetes and Chronic Periodontitis

Table 1

Comparison of groups by tumor necrosis factor-α, interleukin-6, and visfatin levels in gingival crevicular fluid.

	Group 1	Group 2	Group 3	Group 4	One-way ANOVA test		Post hoc analysis
						value	P1	P2	P3	P4	P5	P6
TNF-α	46.20 ± 12.9	158.8 ± 26	98.9 ± 51.5	44 ± 12	32.285	0.001	0.000	0.006	0.698	0.004	0.000	0.004
IL-6	113 ± 27	251.6 ± 60	226.9 ± 62.4	104 ± 46.2	22.453	0.001	0.000	0.000	0.601	0.379	0.000	0.000
Visfatin	284 ± 157.5	2463 ± 865.3	1144.2 ± 2.0	1608.6 ± 286.8	38.667	0.001	0.000	0.000	0.000	0.000	0.008	0.001

ANOVA, analysis of variance; TNF-α, tumor necrosis factor-α; IL-6, interleukin-6. The data are presented as mean ± standard deviation. is statistically significant. P1: comparison between groups 1 and 2; P2: comparison between groups 1 and 3; P3: comparison between groups 1 and 4; P4: comparison between groups 2 and 3; P5: Comparison between groups 2 and 4; P6: comparison between groups 3 and 4.