Impact of Bone Marrow Aspirate Tregs on the Response Rate of Younger Newly Diagnosed Acute Myeloid Leukemia Patients

Table 4

Correlation between dBMA Tregs and AML-related prognostic factors.

	Tregs < 21/μL	Tregs ≥ 21/μL
	Molecular/cytogenetic group^@, (%)				0.020^b
Poor	7 (64)	1 (8)
Intermediate	3 (27)	9 (75)
Good	1 (9)	2 (17)
NPM/FLT3, (%)
NPM^mut	2 (18)	4 (33)	0.64^c
NPM^wt	9 (82)	8 (67)
FLT3 ITD+ or D835+	3 (27)	2 (17)	0.64^c
FLT3^wt	8 (73)	10 (83)
WBC count			0.99^c
<100 × 10e3/μL	10 (91)	10 (83)
≥100 × 10e3/μL	1(9)	2 (17)
De novo AML, (%)			0.155^c
Yes	7 (64)	11 (92)
No	4 (36)	1 (8)

^@According to ELN 2010 [16] [ITD allelic ratio not performed]. ^bChi-square test. ^cFisher exact test. Bold value is statistically significant ().