Herbal Compounds Play a Role in Neuroprotection through the Inhibition of Microglial Activation

Figure 1

Schematic diagram represents prevention of neuronal damage/death by herbal compounds via inhibiting microglial activation through the blockage of related signaling pathway. LPS: lipopolysaccharide; Aβ: amyloid beta; MPTP: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; TBI: traumatic brain injury; SAH: subarachnoid hemorrhage; PI3k/AKT: phosphoinositide 3-kinase/protein kinase B; MAPKs: mitogen-activated protein kinases; NF-κB: nuclear factor-kappa B; JAK/STAT: Janus kinase/signal transducers and activators of transcription; NADPH oxidase: nicotinamide adenine dinucleotide phosphate oxidase; ROS: reactive oxygen species.