|
| Gene symbol | Gene title | FC |
|
| Immune response |
| CCR2 | Chemokine (C-C motif) receptor 2 | −1.48 |
| CXCL1 | Chemokine (C-X-C motif) ligand 1 | 1.81 |
| CXCL13 | Chemokine (C-X-C motif) ligand 13 | −5.52 |
| GATA3 | GATA-binding protein 3 | −6.62 |
| TROVE2 | TROVE domain family, member 2 | −1.64 |
| ICOSLG | Inducible T cell costimulator ligand | 2.51 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) | 2.00 |
| FOXP3 | Forkhead box P3 | 1.49 |
| ULBP1 | UL16-binding protein 1 | −1.77 |
| ITGA4 | Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 1.48 |
| CXCL9 | Chemokine (C-X-C motif) ligand 9 | 1.59 |
| CSF3 | Colony-stimulating factor 3 (granulocyte) | 1.46 |
| IL6 | Interleukin 6 (interferon, beta 2) | 1.51 |
| CD84 | CD84 molecule | 3.40 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 1.77 |
| LAT2 | Linker for activation of T cells family, member 2 | 1.85 |
| C7 | Complement component 7 | 3.11 |
| CCR1 | Chemokine (C-C motif) receptor 1 | 3.27 |
| CCR3 | Chemokine (C-C motif) receptor 3 | 2.80 |
| CFP | Complement factor properdin | 2.92 |
| IL24 | Interleukin 24 | 2.19 |
| IL8 | Interleukin 8 | 1.86 |
| CXCL10 | Chemokine (C-X-C motif) ligand 10 | 1.82 |
| IL1F7 | Interleukin 1 family, member 7 (zeta) | −2.26 |
| IKBKB | Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase beta | −2.25 |
| CCL11 | Chemokine (C-C motif) ligand 11 | 1.96 |
| Type I interferon signaling |
| Cellular response to interferon alpha | |
| FCAR | Fc fragment of IgA, receptor for | 2.15 |
| Type I interferon signaling | |
| IFNA16 | Interferon, alpha 16 | 1.58 |
| STAT1 | Signal transducer and activator of transcription 1, 91 kDa | −1.46 |
| IFNA17 | Interferon, alpha 17 | 1.56 |
| YY1 | YY1 transcription factor | −2.24 |
| IFNA4 | Interferon, alpha 4 | 1.73 |
| IRF8 | Interferon regulatory factor 8 interferon regulatory factor 8 | −1.68 |
| IFNA5 | Interferon, alpha 5 | −2.85 |
| IRF2 | Interferon regulatory factor 2 | 1.58 |
| IFNA8 | Interferon, alpha 8 | 2.23 |
| IRF5 | Interferon regulatory factor 5 | 1.52 |
| IFI6 | Interferon, alpha-inducible protein 6 | 1.56 |
| IFNA6 | Interferon, alpha 6 | 2.08 |
| Positive regulation of interferon alpha production | |
| IRF5 | Interferon regulatory factor 5 | 1.52 |
| Positive regulation of interferon beta production | |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | −1.49 |
| IRF5 | Interferon regulatory factor 5 | 1.52 |
| Negative regulation of interferon beta production | | |
| LILRB1 | Leukocyte immunoglobulin-like receptor, subfamily B, member 1 | −1.60 |
| Positive regulation of Type I interferon production | |
| IFI16 | Interferon, gamma-inducible protein 16 | −1.68 |
| CREBBP | CREB-binding protein (Rubinstein-Taybi syndrome) | 1.51 |
| Negative regulation of Type I interferon production | |
| CYLD | Cylindromatosis (turban tumor syndrome) | −3.04 |
| Gamma interferon signaling |
| Cellular response to Interferon Gamma signaling | |
| FCAR | Fc fragment of IgA, receptor for | 2.15 |
| MRC1 | Mannose receptor, C type 1 | 2.52 |
| SYNCRIP | Synaptotagmin-binding, cytoplasmic RNA-interacting protein | −1.69 |
| CCL8 | chemokine (C-C motif) ligand 8 | 1.63 |
| Interferon gamma signaling | |
| STAT1 | Signal transducer and activator of transcription 1, 91 kDa | −1.46 |
| MID1 | Midline 1 (Opitz/BBB syndrome) | −1.99 |
| HLA-DRB4 | Major histocompatibility complex, class II, DR beta 4 | 2.39 |
| SDK1 | Sidekick homolog 1 (chicken) | 1.61 |
| IFNGR1 | Interferon gamma receptor 1 interferon gamma receptor 1 | 1.67 |
| Negative regulation of gamma interferon production | |
| LILRB1 | Leukocyte immunoglobulin-like receptor, subfamily B, member 1 | −1.60 |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 | −1.69 |
| IL10 | Interleukin 10 | −3.56 |
| Positive regulation of gamma interferon production | |
| FOXP3 | Forkhead box P3 | 1.49 |
| IL1B | Interleukin 1, beta | 1.80 |
| Toll-like receptor signaling |
| TANK | TRAF family member-associated NFKB activator | −1.91 |
| CHUK | Conserved helix-loop-helix ubiquitous kinase | −1.72 |
| ELK1 | ELK1, member of ETS oncogene family | 3.70 |
| MAP3K8 | Mitogen-activated protein kinase kinase kinase 8 | −2.16 |
| TLR6 | Toll-like receptor 6 | 2.43 |
| TLR1 | Toll-like receptor 1 | 1.57 |
| TLR7 | Toll-like receptor 7 | −1.64 |
| MAP3K7 | Mitogen-activated protein kinase kinase kinase 7 | −1.89 |
| LY96 | Lymphocyte antigen 96 | −1.81 |
| NFKB2 | Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 (p49/p100) | 1.54 |
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | −1.82 |
| PTGS2 | Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 1.76 |
| TNFAIP3 | Tumor necrosis factor, alpha-induced protein 3 | 1.73 |
| MAP2K3 | Mitogen-activated protein kinase kinase 3 | 1.59 |
| IKBKB | Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase beta | −2.25 |
| TLR3 | Toll-like receptor 3 | −2.03 |
| IFNB1 | Interferon, beta 1, fibroblast | −1.84 |
| IRAK3 | Interleukin-1 receptor-associated kinase 3 | 1.70 |
| TLR4 | Toll-like receptor 4 | 1.46 |
| IKBKE | Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase epsilon | 2.06 |
| MAP2K2 | Mitogen-activated protein kinase kinase 2 | 1.98 |
| TLR2 | Toll-like receptor 2 | −2.30 |
|
