A Dual-Type L2 11-88 Peptide from HPV Types 16/18 Formulated in Montanide ISA 720 Induced Strong and Balanced Th1/Th2 Immune Responses, Associated with High Titers of Broad Spectrum Cross-Reactive Antibodies in Vaccinated Mice

Table 2

Group of mice immunized with the dual-type 11-88 L2 peptide in different adjuvant formulations.

Groups	Immunogen
G1	(HPV 16) 11-88 × 1 + (HPV 18) 11-88 × 1 in alum
G2	(HPV 16) 11-88 × 1 + (HPV 18) 11-88 × 1 in CFA/IFA
G3	(HPV 16) 11-88 × 1 + (HPV 18) 11-88 × 1 in MF59
G4	(HPV 16) 11-88 × 1 + (HPV 18) 11-88 × 1 in M720
G5	(HPV 16) 11-88 × 1 + (HPV 18) 11-88 × 1 in M50
G6 (control groups)	Adjuvants (alum, MF59, M720, and M50)
G7 (control group)	PBS

CFA/IFA, alum, MF59, and M720 and M50 denote the complete/incomplete Freund, aluminum hydroxide, MF59, and Motanide ISA 720 and ISA 50V adjuvants, respectively. Control groups are deprived from antigen.