Journal of Immunology Research / 2018 / Article / Tab 2

Research Article

Enhanced Suppressive Activity of Regulatory T Cells in the Microenvironment of Malignant Pleural Effusions

Table 2

Correlations between analyzed genes in three groups of pleural effusions.

PEsMPEsnMPEs

FOXP3/CD28rs = 0.794452
rs = 0.828070
rs = 0.652747
FOXP3/GITRrs = 0.386698
rs = 494737
rs = 0.116484
FOXP3/CTLA-4rs = 0.749332
rs = 0.743860
rs = 0.665934
CD28/GITRrs = 0.233957
rs = 0.412281
rs = −0.468132
CD28/CTLA-4rs = 0.892714
rs = 0.868421
rs = 0.617582
GITR/CTLA-4rs = 0.495655
rs = 0.650877
rs = 0.178022

Correlations between relative mRNA expression of FOXP3, CD28, CTLA-4, and GITR genes in CD4+CD25+ cells isolated from: PEs = all pleural effusions; MPEs = malignant pleural effusions with malignant cells; and nMPEs = nonmalignant pleural effusions.