Research Article
Decreased Frequencies of Th17 and Tc17 Cells in Patients Infected with Avian Influenza A (H7N9) Virus
Figure 5
Th17 cells were the principal sources of IL-17A among PBMCs obtained from H7N9 patients and infected with the H7N9 virus in vitro. (a) Isolated PBMCs were initially gated for lymphocytes and IL-17A+ cells, and the proportions of CD4+CD8-, CD4-CD8+, and CD4-CD8- cells were then analyzed. (b) The proportions of IL-17A+CD4+CD8- cells (Th17), IL-17A+CD4-CD8+ cells (Tc17), and IL-17A+CD4-CD8- cells from HC and H7N9 patients in the acute and recovery phases, respectively (). (c) The proportions of IL-17A+CD4+CD8- cells (Th17), IL-17A+CD4-CD8+ cells (Tc17), and IL-17A+CD4-CD8- cells from healthy volunteers infected with the H7N9 virus in vitro at the indicated time points. and .
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