Elevated Serum IgG Levels Positively Correlated with IL-27 May Indicate Poor Outcome in Patients with HBV-Related Acute-On-Chronic Liver Failure

Figure 5

Accuracy of IgG levels was compared to other parameters in predicting the 3-month mortality of HBV-ACLF patients. The area under the ROC curve (AUC) for IgG levels was 0.752 (95% confidence interval: 0.562-0.891, ). Interestingly, no significant differences existed between AUC values obtained using IgG levels and those obtained with IL-27 levels (0.824, ), MELD score (0.870, ), MELD-Na score (0.854, ), or CLIF-C ACLF score (0.671, ) in HBV-ACLF patients.