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Journal of Immunology Research
Volume 2019, Article ID 1629258, 7 pages
https://doi.org/10.1155/2019/1629258
Research Article

Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity

1Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan
2Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan
3Dharma Husada Nursing Academy, Kediri, East Java, Indonesia
4Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan
5Division of Infectious Diseases, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, Taipei 110, Taiwan
6Division of Infectious Diseases, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 110, Taiwan
7School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei 110, Taiwan
8Pulmonary Research Center, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan
9Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan
10Research Center of Thoracic Medicine, Taipei Medical University, Taipei 110, Taiwan

Correspondence should be addressed to Chiou-Feng Lin; wt.ude.umt@4102nilfc

Received 19 February 2019; Revised 2 April 2019; Accepted 10 April 2019; Published 30 May 2019

Guest Editor: Antonio Rivero

Copyright © 2019 Dyah Ika Krisnawati et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. W. Murray, “Interferon-gamma and host antimicrobial defense: current and future clinical applications,” The American Journal of Medicine, vol. 97, no. 5, pp. 459–467, 1994. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Pieters, “Mycobacterium tuberculosis and the macrophage: maintaining a balance,” Cell Host & Microbe, vol. 3, no. 6, pp. 399–407, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. S. K. Browne, P. D. Burbelo, P. Chetchotisakd et al., “Adult-onset immunodeficiency in Thailand and Taiwan,” The New England Journal of Medicine, vol. 367, no. 8, pp. 725–734, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. S. K. Browne, “Anticytokine autoantibody–associated immunodeficiency,” Annual Review of Immunology, vol. 32, no. 1, pp. 635–657, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. J. L. Flynn, J. Chan, K. J. Triebold, D. K. Dalton, T. A. Stewart, and B. R. Bloom, “An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection,” Journal of Experimental Medicine, vol. 178, no. 6, pp. 2249–2254, 1993. View at Publisher · View at Google Scholar · View at Scopus
  6. K. Schroder, P. J. Hertzog, T. Ravasi, and D. A. Hume, “Interferon-γ: an overview of signals, mechanisms and functions,” Journal of Leukocyte Biology, vol. 75, no. 2, pp. 163–189, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. M. A. Gordon, D. L. Jack, D. H. Dockrell, M. E. Lee, and R. C. Read, “Gamma interferon enhances internalization and early nonoxidative killing of Salmonella enterica serovar Typhimurium by human macrophages and modifies cytokine responses,” Infection and Immunity, vol. 73, no. 6, pp. 3445–3452, 2005. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Herbst, U. E. Schaible, and B. E. Schneider, “Interferon gamma activated macrophages kill mycobacteria by nitric oxide induced apoptosis,” PLoS One, vol. 6, no. 5, article e19105, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. P. Wongkulab, J. Wipasa, R. Chaiwarith, and K. Supparatpinyo, “Autoantibody to interferon-gamma associated with adult-onset immunodeficiency in non-HIV individuals in Northern Thailand,” PLoS One, vol. 8, no. 9, article e76371, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. P. Phoompoung, N. Ankasekwinai, M. Pithukpakorn et al., “Factors associated with acquired anti IFN-γ autoantibody in patients with nontuberculous mycobacterial infection,” PLoS One, vol. 12, no. 4, article e0176342, 2017. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Y. Chi, C. C. Chu, J. P. Liu et al., “Anti-IFN-γ autoantibodies in adults with disseminated nontuberculous mycobacterial infections are associated with HLA-DRB116:02 and HLA-DQB105:02 and the reactivation of latent varicella-zoster virus infection,” Blood, vol. 121, no. 8, pp. 1357–1366, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Pithukpakorn, E. Roothumnong, N. Angkasekwinai et al., “HLA-DRB1 and HLA-DQB1 are associated with adult-onset immunodeficiency with acquired anti-interferon-gamma autoantibodies,” PLoS One, vol. 10, no. 5, article e0128481, 2015. View at Publisher · View at Google Scholar · View at Scopus
  13. C. H. Lin, C. Y. Chi, H. P. Shih et al., “Identification of a major epitope by anti-interferon-γ autoantibodies in patients with mycobacterial disease,” Nature Medicine, vol. 22, no. 9, pp. 994–1001, 2016. View at Publisher · View at Google Scholar · View at Scopus
  14. D. I. Krisnawati, Y. C. Liu, Y. J. Lee et al., “Functional neutralization of anti-IFN-γ autoantibody in patients with nontuberculous mycobacteria infection,” Scientific Reports, vol. 9, no. 1, 2019. View at Publisher · View at Google Scholar
  15. M. Benoit, B. Desnues, and J. L. Mege, “Macrophage polarization in bacterial infections,” The Journal of Immunology, vol. 181, no. 6, pp. 3733–3739, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. A. C. Labonte, A.-C. Tosello-Trampont, and Y. S. Hahn, “The role of macrophage polarization in infectious and inflammatory diseases,” Molecules and Cells, vol. 37, no. 4, pp. 275–285, 2014. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Daigneault, J. A. Preston, H. M. Marriott, M. K. B. Whyte, and D. H. Dockrell, “The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages,” PLoS One, vol. 5, no. 1, article e8668, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Genin, F. Clement, A. Fattaccioli, M. Raes, and C. Michiels, “M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide,” BMC Cancer, vol. 15, no. 1, p. 577, 2015. View at Publisher · View at Google Scholar · View at Scopus
  19. D. Y. S. Vogel, J. E. Glim, A. W. D. Stavenuiter et al., “Human macrophage polarization in vitro: maturation and activation methods compared,” Immunobiology, vol. 219, no. 9, pp. 695–703, 2014. View at Publisher · View at Google Scholar · View at Scopus
  20. A. I. Rovetta, D. Pena, R. E. Hernandez Del Pino et al., “IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis,” Autophagy, vol. 10, no. 12, pp. 2109–2121, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. C. Doig, A. L. Seagar, B. Watt, and K. J. Forbes, “The efficacy of the heat killing of Mycobacterium tuberculosis,” Journal of Clinical Pathology, vol. 55, no. 10, pp. 778-779, 2002. View at Publisher · View at Google Scholar · View at Scopus
  22. K. Rattanathammethee, K. Chawansuntati, R. Chaiwarith, J. Praparattanapan, K. Supparatpinyo, and J. Wipasa, “Dot enzyme-linked immunosorbent assay strip as a screening tool for detection of autoantibody to interferon gamma in sera of suspected cases of adult-onset immunodeficiency,” Journal of Clinical Laboratory Analysis, vol. 32, no. 7, article e22460, 2018. View at Publisher · View at Google Scholar · View at Scopus
  23. K. Shima, T. Sakagami, Y. Tanabe et al., “Novel assay to detect increased level of neutralizing anti-interferon gamma autoantibodies in non-tuberculous mycobacterial patients,” Journal of Infection and Chemotherapy, vol. 20, no. 1, pp. 52–56, 2014. View at Publisher · View at Google Scholar · View at Scopus
  24. P. Chetchotisakd and S. Anunnatsiri, “Linezolid in the treatment of disseminated nontuberculous mycobacterial infection in anti-interferon-gamma autoantibody-positive patients,” Southeast Asian Journal of Tropical Medicine and Public Health, vol. 45, no. 5, pp. 1125–1131, 2014. View at Google Scholar
  25. Y. Koizumi, T. Sakagami, N. Nishiyama et al., “Rituximab restores IFN-γ-STAT1 function and ameliorates disseminated Mycobacterium avium infection in a patient with anti-interferon-γ autoantibody,” Journal of Clinical Immunology, vol. 37, no. 7, pp. 644–649, 2017. View at Publisher · View at Google Scholar · View at Scopus
  26. P. Chetchotisakd, S. Anunnatsiri, R. Nanagara, A. Nithichanon, and G. Lertmemongkolchai, “Intravenous cyclophosphamide therapy for anti-IFN-gamma autoantibody-associated Mycobacterium abscessus infection,” Journal of Immunology Research, vol. 2018, Article ID 6473629, 7 pages, 2018. View at Publisher · View at Google Scholar · View at Scopus
  27. J. Wipasa, R. Chaiwarith, K. Chawansuntati, J. Praparattanapan, K. Rattanathammethee, and K. Supparatpinyo, “Characterization of anti-interferon-γ antibodies in HIV-negative immunodeficient patients infected with unusual intracellular microorganisms,” Experimental Biology and Medicine, vol. 243, no. 7, pp. 621–626, 2018. View at Publisher · View at Google Scholar · View at Scopus