The Nod2 Agonist Muramyl Dipeptide Cooperates with the TLR4 Agonist Lipopolysaccharide to Enhance IgG2b Production in Mouse B Cells

Figure 1

MDP sustains B cell viability in vitro, but MDP itself hardly induces B cell proliferation. Resting B cells were stimulated with the indicated MDP concentrations. After 2 and 3 days of culture, cell viability was measured by (a) EZ-Cytox assay and (b) cell proliferation was measured by CFSE assay. Data shown are representative of two independent experiments.

(a)

(b)