Research Article

Functional Polymorphisms and Gene Expression of TLR9 Gene as Protective Factors for Nasopharyngeal Carcinoma Severity and Progression

Table 5

Relative expression of TLR9 mRNA according to NPC clinicopathological parameters at diagnosis.

NPC clinicopathological parameters ()Median of TLR9 expression (-03) valuea

Age0.696
(17)2.15
(33)2.24
Sex0.419
 Women (14)2.40
 Men (36)2.01
Tumor size0.013
 T1-T2-T3 (36)2.52
 T4 (13)1.35
Lymph node0.469
 N0 (5)3.13
 N+ (44)2.11
Metastasis0.653
 M0 (42)2.20
 M+ (4)1.94
Clinical stage0.0374
 SI-SII (6)3.46
 SIII-SIV (41)2.03

a: Mann-Whitney’s test.