| | Tissues of origin | Gene localization | Sugars | PAMPs | Endogenous/artificial ligands | Pathogen interactions |
| | Human | | M-ficolin | Cell surface, serum | 9q34 | GlcNAc, GalNAc, LacNAc, SiaLacNAc, CysNAc, sialic acid, gangliosides | Ebola virus glycoprotein, chitin, β-1, 3-glucans | Acetylated human albumin CD43 | S. agalactiae, S. aureus, S. pneumoniae, S. mitis, E. coli, IAV, T. cruzi, Zaire Ebola virus, A. fumigatus | | L-ficolin | Serum | 9q34 | GlcNAc, GalNAc, ManNAc, CysNAc, GlyNAc, NeuNAc, acetylcholine, elastin | β-1, 3-glucans, N-glycans, HA, neuraminidase, teichoic acid, LPS | Acetylcholine, elastin, corticosteroids | S. aureus, S. pyogenes, S. agalactiae, B. subtilis, S. typhimurium, E. coli, S. pneumoniae, L. monocytogenes, M. bovis BCG, M. tuberculosis, M. smegmatis, E. faecalis, A. fumigatus, HCV, IAV, T. cruzi, G. intestinalis, Leptospira biflexa, Pasteurella pneumotropica | | H-ficolin | Serum, bronchus, alveolus, bile | 1p36.11 | GlcNAc, GalNAc, fucose, glucose, acetylsalicylic acid, sialic acid, D-mannose, GlyNAc, CysNAc | LPS, PSA, Ag85 | — | S. typhimurium, S. minnesota, E. coli O111, Hafnia alvei, A. fumigatus, IAV, T. cruzi, G. intestinalis, P. pneumotropica, M. bovis BCG, M. kansasii | | Rodent | | Ficolin-A | Serum | 2A3 | GlcNAc, GalNAc | LPS | Fibrinogen | S. pneumoniae, S. aureus, E. coli O157:H7, P. aeruginosa, C. neoformans, A. fumigatus, A. flavus, A. terreus, A. niger | | Ficolin-B | Peritoneal MØ | 2A3 | GlcNAc, GalNAc, LacNAc, SiaLacNAc, LDL, NeuNAc | — | LDL, fetuin | Nk |
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BM, bone marrow; GlcNAc, N-acetylglucosamine; GalNAc, N-acetylgalactosamine; LacNAc, N-acetyllactosamine; SiaLacNAc, sialylated N-acetyllactosamine; CysNAc, N-acetylcysteine; ManNAc, N-acetylmannosamine; GlyNAc, N-acetylglycine; NeuNAc, N-acetylneuraminic acid; HA, hemagglutinin; LPS, lipopolysaccharide; IAV, influenza A virus; LDL, low-density lipoprotein; LTA, lipoteichoic acid; HCV, hepatitis C virus; Nk, not known.
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