Differential Expression of IFN-γ, IL-10, TLR1, and TLR2 and Their Potential Effects on Downgrading Leprosy Reaction and Erythema Nodosum Leprosum

Table 3

Correlation matrix among dependent and independent variables of the reaction-free leprosy patients group, based on Pearson’s correlation.

Variables	Reaction-free group
	IFN-γ			Toll-like receptor 1			Toll-like receptor 2
		CI (95%)	value		CI (95%)	value		CI (95%)	value
Number of injured nerves	0.04	-0.68–0.72	0.905	-0.20	-0.77–0.62	0.576	-0.18	-0.63–0.76	0.606
Number of skin lesions	-0.35	-0.85–0.47	0.265	-0.26	-0.74–0.67	0.473	-0.47	-0.86–0.43	0.142
DG	-0.06	-0.78–0.61	0.869	-0.09	-0.82–0.54	0.795	-0.11	-0.71–0.70	0.741
Age	0.24	-0.55–0.81	0.513	0.07	-0.64–0.76	0.845	-0.06	-0.62–0.77	0.865
Toll-like receptor 1	0.73	0.03–0.94	0.023				0.87	0.43–0.98	0.002
Toll-like receptor 2	0.78	0.45–0.98	0.013	0.87	0.43–0.98	0.002
IL-10	0.66	-0.13–0.95	0.053	0.32	-0.62–0.84	0.401	0.43	-0.55–0.87	0.249
IFN-γ				0.74	0.03–0.94	0.023	0.78	0.45–0.98	0.013
IL-4	-0.31	-0.85–0.47	0.384	-0.25	-0.84–0.49	0.485	-0.34	-0.86–0.44	0.309
TNF-α	-0.28	-0.85–0.45	0.426	-0.31	-0.87–0.38	0.386	-0.36	-0.87–0.41	0.279
Anti-LAM	-0.29	-0.84–0.49	0.419	-0.28	-0.85–0.47	0.429	-0.28	-0.82–0.54	0.399
Anti-PGL-I	-0.51	-0.89–0.31	0.132	-0.33	-0.78–0.62	0.357	-0.35	-0.86–0.42	0.294
Bacterial index	-0.45	-0.87–0.38	0.197	-0.38	-0.81–0.55	0.283	-0.74	-0.89–0.33	0.144

: Pearson’s correlation coefficient; CI (95%): confidence interval of 95%, DG: disability grade; IL-10: interleukin 10; IFN-γ: interferon gamma; IL-4: interleukin 4; TNF-α: tumor necrosis factor (alpha); anti-LAM: anti-lipoarabinomannan antibody; anti-PGL-I: anti-phenolic glycolipid-1 antibody. Diagnostic data.