Research Article
Enhancement of Immune Responses by Guanosine-Based Particles in DNA Plasmid Formulations against Infectious Diseases
Table 1
Mouse groups for the immunization studies.
| |||||||||||||||||||||||||||||||||||||||
The dosages of injections for experimental groups (pDNAs alone or pDNAs+SHS) were as follows: 50 μL per leg of pDNA preparation (1 μg/μL of pDNA in 100 μL PBS) or 50 μL per leg of pDNA+SHS preparation (1 μg/μL of of SHS in 100 μL PBS). Control mouse groups included those to determine basal responses (naïve) and those receiving 50 μL per leg of backbone plasmid (1 μg/μL pVAX1 in 100 μL PBS) and 50 μL per leg of SHS particles alone (0.1515 mM SHS in 100 μL PBS) to demonstrate nonantigen-specific immune responses. |