Research Article

Cross-Disease Innate Gene Signature: Emerging Diversity and Abundance in RA Comparing to SLE and SSc

Table 1

Demographic and clinical characteristics of enrolled patients.

RA ()SLE ()SSc ()

Female/male26/1024/415/7
Age (years) mean (min-max)57.5 (39-80)40.1 (19-67)58.0 (38-77)
Duration of the disease (years) mean (min-max)18.1 (9-50)10.0 (1-20)5.4 (0-21)
Medications (% ())
 Steroids89 (32)82 (23)96 (21)
 NSAIDs78 (28)14 (4)0 (0)
 Methotrexate83 (30)14 (4)9 (2)
 Other DMARDs36 (13)100 (28)73 (16)
 Biologics39 (14)0 (0)0 (0)
Relative white blood count (%)
Lymphocytes (mean (95% CI))24.9 (20.5-29.3)22.9 (18.5-27.3)21.4 (17.5-25.4)
Neutrophils (mean (95% CI))62.9 (57.9-67.9)67.1 (61.6-72.6)67.3 (62.5-72.2)
Monocytes (mean (95% CI))8.9 (7.9-9.9)8.5 (7.1-9.9)9.2 (7.9-10.4)

NSAIDs: nonsteroidal anti-inflammatory drugs; DMARDs: disease-modifying antirheumatic drugs; CI: confidence interval. Other DMARDs taken were hydroxychloroquine (RA/SLE/SSc; ), leflunomide (8/0/0), sulfasalazine (2/0/0), azathioprine (0/8/12), mycophenolate mofetil (0/6/0), cyclophosphamide (0/3/3), and cyclosporine (0/1/1).