Immunobiotics Beneficially Modulate TLR4 Signaling Triggered by Lipopolysaccharide and Reduce Hepatic Steatosis In Vitro

Figure 6

Modulation of the expression of TLR negative regulators by total cellular fluid of LABs in free fatty acid-treated HepG2 cells. HepG2 cells were prestimulated with total cellular fluid of LABs followed by stimulation with LPS for 3 h and 12 h. The expression of A20, SIGIRR, Tollip, and IRAK-M1 was determined by RT-PCR. HepG2 cell treated with LPS was used as control. Different superscript letters indicate significant differences at the 0.05 level.