Journal of Immunology Research / 2019 / Article / Fig 4

Review Article

Novel Immune Microlens Imaging for Detection of Antigen and Antibody

Figure 4

Refractive index changes with antigen-antibody reactions. (a) Relationships between the refractive index of IFN-γ or PAP antigen-antibody reaction and its time. (b) Relationships between and KLK6 or CRP antigen concentrations were determined, respectively, when its monoclonal Ab or polyclonal Ab was added to corresponding antigen. (c) Relationships between the and HCG and cTnI or FABP antigen concentrations were analyzed, respectively, when its capture Ab or probing Ab was added to corresponding antigen. Ag: antigen; Ab: antibody; : change of refractive index; IFN-γ: interferon-γ; PAP: placenta alkaline phosphatase; KLK6: kallikrein 6; HCG: human chorionic gonadotropin; cTnI: cardiac troponin; FABP: fatty acid binding proteins; CRP: C-reactive protein.

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