Journal of Immunology Research / 2019 / Article / Fig 4

Research Article

MTOR-Mediated Autophagy Is Involved in the Protective Effect of Ketamine on Allergic Airway Inflammation

Figure 4

Effect of ketamine on autophagy in the lungs from mice sensitized to OVA. (a, b) Electron micrographs and quantification of autophagic vacuoles. (c–j) With Western blot, MTOR, p-MTOR, LC-3I, LC-3II, and Beclin-1 were determined and quantified. (k, l) With immunohistochemistry (magnification, ×200), p-MTOR were determined and quantified. Data are expressed as the mean ± SD of six mice per group. , , and versus the control group; and versus the OVA group.