Calcitriol Inhibits the Proliferation of Triple-Negative Breast Cancer Cells through a Mechanism Involving the Proinflammatory Cytokines IL-1β and TNF-α

Table 2

IL-β and TNF-α secretion induced by calcitriol and its analogue in breast cancer cell lines.

		SUM-229PE		HCC1806		MCF7
		IL-1β (pg/ml)	TNF-α (pg/ml)	IL-1β (pg/ml)	TNF-α (pg/ml)	IL-1β (pg/ml)	TNF-α (pg/ml)
Calcitriol (nM)	0
	1
	10
	100
EB1089 (nM)	1
	10
	100

Results are expressed as the cytokine secretion of triplicate determinations and represent at least three different experiments. vs. nontreated cells (0).