KIR/HLA Gene Profile Implication in Systemic Sclerosis Patients from Mexico
Table 5
Clinical manifestations and KIR genes.
Sclerodactyly (%) ()
Musculoskeletal damage (%) ()
Raynaud’s phenomenon (%) ()
Inflamed fingers (%) ()
Telangiectasias (%) ()
Digital ulcers (%) ()
2DL2
63.6 (28)
58.5 (24)
60.0 (21)
55.9 (19)
59.3 (16)
70.0 (14)
2DS4full
34.1 (15)
31.7 (13)
37.1 (13)
35.3 (12)
44.4 (12)
45.0 (9)
2DS4del
25.0 (11)
24.4 (10)
31.4 (11)
29.4 (10)
22.2 (6)
45.0 (4)
2DS4full/del
22.7 (10)
26.8 (11)
17.1 (6)
17.6 (6)
22.2 (6)
45.0 (4)
2DS4neg
18.2 (8)
17.1 (7)
14.3 (5)
17.6 (6)
11.1 (3)
15.0 (3)
KIR2DS4full/del includes individuals with a copy of the full gene and del variant; 2DS4full includes individuals with one or two copies of the full gene; 2DS4del includes individuals with one or two copies of the del variant; and 2DS4neg includes individuals without KIR2DS4.
