CD38 Deficiency Downregulates the Onset and Pathogenesis of Collagen-Induced Arthritis through the NF-κB Pathway

Figure 4

Alteration of proinflammatory cytokines in BMDCs generated over 7 days from CD38^-/- CIA mice. DCs were cultured from the bone marrow of the WT and CD38^-/- CIA mice, and the mRNA was extracted from the WT and CD38^-/- DCs. The expressions of IL-1β (a), TNF-α (b), IL-4 (c), and IL-10 (d) were detected by RT-qPCR. Results show average levels of those genes expressed as OD ( per group/experiment) ().

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