Journal of Immunology Research / 2019 / Article / Tab 1

Research Article

Expressions of MMP-12, TIMP-4, and Neutrophil Elastase in PBMCs and Exhaled Breath Condensate in Patients with COPD and Their Relationships with Disease Severity and Acute Exacerbations

Table 1

Clinical characteristics and demographics of the study participants.

ParametersHealthy controls ()COPD patients ()

Age (years)
Sex (M/F)17/1123/12
Disease duration (years)
Smoking history (nonsmoker/ex-smoker/current smoker)21/7/03/25/7
Number taking (ICS/LABA/LAMA)0/0/030/27/29
Pulmonary function
 FEV1 (% predicted)
 FVC (% predicted)
 FEV1/FVC ratio (% predicted)
 DLco (% predicted)

Parametric parameters were presented as . Differences between healthy controls and COPD patients ( and ). values were based on unpaired -tests. was considered significant. COPD: chronic obstructive pulmonary disease; ICS: inhaled corticosteroid; LABA: inhaled long-acting beta adrenergic antagonist; LAMA: inhaled long-acting antimuscarinic agonist; FEV1: forced expiratory volume in 1 second; DLCO: carbon monoxide diffusion capacity; FVC: forced vital capacity; PBMC: peripheral blood mononuclear cells; pred: predicted.

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