Kidney Transplant Outcome Is Associated with Regulatory T Cell Population and Gene Expression Early after Transplantation

Table 5

CD8⁺CD28⁻ T cell absolute and related counts in examined groups of recipients in relation to controls and hemodialysed patients.

Cells	Control group	Dialysis group	value dialysis vs. control	Time from KTx	Mean ± SD (median; IQR)	value KTx vs. control	value KTx vs. dialysis
T CD8 CD28−/μl	(43.1; 14.0–85.4)	(86; 14–85.4)	0.048	1 w.	(15; 5–30)	0.008	<0.001
				1 m.	(35; 15–89)	0.663	0.042
				3 m.	(61; 48–185)	0.135	0.509
				6 m.	(122; 75–363)	0.003	0.231
				12 m.	(216; 89–393)	<0.001	0.054
T CD8 CD28− %T	(3.2; 1.2–6.0)	(9.7; 5.6–15.5)	0.004	1 w.	(2.4; 1.0–5.0)	0.411	<0.001
				1 m.	(2.4; 1.0–7.9)	0.772	0.004
				3 m.	(5.5; 3.7–10.5)	0.067	0.409
				6 m.	(11.4; 6.0–18.5)	<0.001	0.320
				12 m.	(14.7; 7.1–22.6)	<0.001	0.239
				y.	(7.2; 3.7–13.6)	0.010	0.461
T CD8 CD28− % T CD8	(22.9; 17.1–51.0)	(34.6; 17.1–51)	0.244	1 w.	(32.1; 16.6–41.1)	0.292	1.000
				1 m.	(29.9; 17.8–52.2)	0.570	0.892
				3 m.	(51.2; 31.8–62.4)	0.002	0.040
				6 m.	(56.9; 45.1–73.6)	<0.001	<0.001
				12 m.	(59.3; 42.3–73.7)	<0.001	<0.001
				y.	(42.0; 26.9–58.3)	0.010	0.123